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Publisher: Actualizacion sobre los efectos adversos durante la terapia con dieta cetogenica en la epilepsia refractaria uccion. Request PDF on ResearchGate | Presentación de un caso de aplicación de la dieta cetogénica en la epilepsia refractaria | The case of a 2-year-old male patient. Download Citation on ResearchGate | On Dec 1, , Nerea Gorria Redondo and others published Dieta cetogénica como opción terapéutica en la epilepsia.

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The keywords selected for the study included epilepsy, status epilepticus, pilocarpine, oxidative stress, reactive oxygen species, mitochondrial dysfunction.

Services on Demand Journal. Actualizacion sobre los efectos adversos durante la terapia con dieta cetogenica en la epilepsia refractaria pediatrica.

The most frequent adverse effects that may occur cetogencia in acute form or in cteogenica stages are described, and tools that cetogebica be used in their management and prevention during treatment are proposed for paediatricians and ketogenic diet teams. Epilepsy is a neurological disorder more common, being defined as a condition of spontaneous recurrent seizures.

An important relationship exists between free radicals and antioxidant enzymes in epileptic phenomena and reactive oxygen species ROS have been implicated in neurodegeneration induced by crises. The ketogenic diet is a non-pharmacological treatment that has been used as a therapeutic alternative for the management of refractory epilepsy since It is a nutrition plan that is imbalanced in terms of both macro- and micro-nutrients, which can give rise to nutritional deficits in energy, proteins, minerals and vitamins, as well as an excess of lipids.

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Evidence of activity of KD in mitochondrial dysfunction, as epilepsy, are many and clearly demonstrate the beneficial effects of the therapy.

O papel da dieta cetogênica no estresse oxidativo presente na epilepsia experimental

How to cite this article. The KD modulates mitochondrial bioenergetic, decreases the formation of ROS, increases the antioxidant capacity and also prevents changes in mitochondrial DNA.

Se describen los efectos adversos mas frecuentes que se presentan en forma aguda o tardiamente, y se brindan herramientas para su manejo y prevencion durante el tratamiento para pediatras y equipos de dieta cetogenica. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.

Se trata de un plan alimentario desequilibrado tanto en macro como en micronutrientes, que puede causar deficits nutricionales en energia, proteinas, minerales y vitaminas, y exceso de lipidos, con riesgo de ocasionar efectos secundarios no deseados tanto en el inicio del tratamiento como de forma tardia. Algunos efectos adversos son de dificil interpretacion, y pueden ser manifestacion por afectacion a diferentes niveles del organismo, poniendo en duda si son secundarios a la dieta, a la medicacion antiepileptica o a intercurrencias del propio paciente.

Es importante seguir el protocolo de frecuencia de estudios y evaluaciones para detectar y prevenir estos efectos, y consultar a centros de referencia evaluando el coste-beneficio de continuar o no el tratamiento. This review aimed to investigate the relationship between oxidative stress and epilepsy, highlighting the effect of the ketogenic diet under experimental conditions.

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Dieta cetogénica

La dieta cetogenica es una terapia no farmacologica que se ha usado como alternativa para el tratamiento de la epilepsia refractaria desde There is therefore a risk of it causing undesirable side effects both at the outset and cetogenicw later stages of the treatment. Some adverse effects are difficult to interpret and may manifest due to involvement epilpesia different levels of the organism, thereby arousing doubts as to whether they are caused by the diet, the antiepileptic medication or by the patient’s own intercurrent complications.

It is important to follow the study and evaluation frequency protocol in order to detect and prevent these effects, as well as to consult reference centres in fieta to evaluate the cost-benefit of continuing the treatment or not.

Dietary therapy has been used, such as the ketogenic epilelsia KDwhich is rich in fat and low in carbohydrates and used by more than eight decades for the treatment of refractory epilepsy, especially in children. The role of the ketogenic diet on oxidative stress present in experimental epilepsy. Garrahan, Buenos Aires, Argentina.