INFeD® improved the hemoglobin response to erythropoietic therapy in have been reported after administration of iron dextran injection, the drug should be. iron dextran – Drug Summary. Jump to INFeD Intramuscular Inj Sol: 1mL, 50mg . INFeD: INFeD is administered by intramuscular or intravenous injection. Allergan, Inc.: Intravenous or intramuscular injections of INFeD are indicated for treatment of patients with documented iron deficiency in whom.
|Published (Last):||23 April 2016|
|PDF File Size:||4.74 Mb|
|ePub File Size:||1.84 Mb|
|Price:||Free* [*Free Regsitration Required]|
Isoproterenol or similar beta-agonist agents may be required in these patients. Normal hemoglobin males and females over 15 kg 33 lbs. Major Deferasirox chelates iron and is indicated as a treatment of iron toxicity or overdose. Patients should be monitored for signs and symptoms of anaphylactic-type reactions during all iron dextran administrations.
Moderate The concomitant use of angiotensin-converting enzyme inhibitors ACE inhibitors pacmage iron dextran may increase the risk for anaphylactic-type reactions. Ankylosing spondylitis, asthma, atopy, rheumatoid arthritis, systemic lupus erythematosus SLE. Consider the benefits of lackage, the risk of potential infant drug exposure, and the risk of an untreated or inadequately treated condition.
After administration of packaeg dextran complex, evidence of a therapeutic response can be seen in a few days as an increase in the reticulocyte count.
If test dose uneventful, give the remainder of the total dose as 50 mg of elemental iron per day IM or slow IV until the total calculated dose is nifed. Consult specialized references for amount of test dose to be given.
Iron dextran (INFeD)
Inadequate iron stores will interfere with the therapeutic response to these agents e. Patients with hepatic disease should receive iron dextran with caution.
Adults and Children over 15 kg 33 lbs: Infants and Children 4 months and older weighing less than 15 kg.
Major In general, oral mineral supplements should not be given since they may block the oral absorption of trientine. If test dose uneventful, doses of 1. Inject deeply into the upper outer quadrant of the buttock gluteus maximus only using a 2- or 3-inch, or gauge needle. The table and formula described under I. The use of iron dextran to prevent iron deficiency in patients knfed long-term parenteral nutrition support is controversial; some experts advocate the use of iron to treat a deficiency if it occurs vs.
U.S. Prescribing Information Disclaimer
The first stage involves an inflammatory reaction at the site of injection which aids the passage of the drug into the lymphatic system. Iron dextran should be administered to pregnant women only if the benefits outweigh the potential risks to the fetus. The table and accompanying formula are applicable for dosage determinations only in patients with iron deficiency anemia; they are not to be used for dosage determinations in patients requiring iron replacement for blood loss.
Therefore, administration inswrt subsequent test doses during therapy should be considered.
Dilution Iron Dextran (imferon ®) – GlobalRPH
Cardiovascular adverse effects may also occur with iron dextran therapy, and do not necessarily indicate hypersensitivity. Furthermore, concomitant use of angiotensin-converting enzyme inhibitors may increase the risk for serious reactions to iron dextran.
Parenterally administered iron does not give a faster response compared to oral administration, therefore, the rate of recovery from anemia should be the same. Iron dextran is contraindicated for use in patients with anemia not associated with iron deficiency.
Anaphylaxis and other hypersensitivity reactions have been reported after uneventful test doses as well as therapeutic doses of iron dextran injection. Iron supplementation may be needed before and during therapy e. In general, iron supplementation should not begin in premature infants until adequate innfed E is supplied in the diet; human nifed milk and modern infant formulas usually supply adequate dietary vitamin Insrt.
There are limits to the volume of iron dextran that may be injected IV undiluted per 24 hours based on patient age and weight; see dosage guidelines. Parenteral iron treatment should be administered only when iron deficiency is not correctable with oral treatment.
The total amount of INFeD in mL required to treat the anemia and replenish iron stores may be approximated as follows:. If test dose uneventful, ;ackage the remainder of the total calculated dose see equation IV over 2 to 6 hours.
Specific guidelines for dosage adjustments in renal impairment are not available; it appears that no dosage adjustments are needed. Adults, Adolescents, and Children weighing more than 15 kg. To restore hemoglobin and replenish iron stores in iron-deficiency anemia due to causes other than blood loss. Send the page ” ” to a friend, relative, colleague or yourself. Your Name Your name is required.
Achieving and maintaining adequate iron stores are essential to attaining an optimal response to MPG-epoetin beta. Total Dose Intravenous Infusion : Unnecessary or prolonged administration of iron may lead to iron overload and consequently the possibility of exogenous hemosiderosis.
Because anaphylactic reactions are insret to occur after uneventful test doses, test doses before subsequent doses should be considered. Parenteral iron dextran therapy is associated with a risk of serious hypersensitivity reactions or anaphylaxis. Children 5 — 15 kg 11 — 33 lbs: Related Drug Information Drug Summary.
There is some concern that intravenously administered iron is not used appropriately by the body.
It would be illogical for a patient to receive both iron supplementation and deferoxamine simultaneously. Since deferiprone has the potential to bind polyvalent cations e. According to the manufacturer, caution should be exercised if iron dextran is administered to a nursing mother.